| 1. | Therefore, greater GPCR selectivity may be obtained by targeting allosteric sites.
|
| 2. | RNR1 contains both allosteric sites, mediating regulation of substrate specificity and activity.
|
| 3. | However, not all inhibitors that bind at allosteric sites are mixed inhibitors.
|
| 4. | Allosteric sites may represent a novel drug target.
|
| 5. | This may be accomplished by binding to the active site or the allosteric site.
|
| 6. | In addition, sGC contains an allosteric site, to which sGC stimulators bind.
|
| 7. | The second form of " non-competitive antagonists " act at an allosteric site.
|
| 8. | The site to which the effector binds is termed the " allosteric site ".
|
| 9. | Under resting conditions, it is thought that chloride is bound to allosteric sites in prestin.
|
| 10. | These allosteric sites are involved in creating the ligand-enzyme specificity seen in most bioactive enzymes.
|
मोबाइल